Publications 1995-2000

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1995 Stathopoulos C., Kalpaxis D. L., and Drainas D. Partial purification and characterization of RNase Ρ from Dictyostelium discoideum. Eur. J. Biochem. 228: 976-980. 1998 Tekos A., Stathopoulos C., and Drainas D. (1998) Bimodal action of the alkaline earth cations on Dictyostelium discoideum ribonuclease Ρ activity. Biochemistry 37: 15474-15480. 1999 Tekos A., Tsagla A., Stathopoulos C., and Drainas D. (1999) Inhibition Dictyostelium discoideum ribonuclease Ρ activity by aminoglycosides. Nucleic Acids Symp. Series…

Publications 2001-2005

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2001 Stathopoulos C., Jacquin-Becker C., Becker H.D., Li T., Ambrogelly A., Longman R. and Söll D. Methanococcus jannaschii Prolyl-Cysteinyl-tRNA synthetase possesses overlapping amino acid binding sites. Biochemistry 40: 46-52. Stathopoulos C., Tekos A., Zarkadis, I. and Drainas D. (2001) Extensive deproteinization of Dictyostelium discoideum RNase Ρ reveals a new catalytic activity. Eur. J. Biochem. 268: 2134-214 Ibba M., Stathopoulos C. and Söll D. . Protein Synthesis: 23 Amino acids and counting. Current Biology 11: 563-565.…

Publications 2006-2010

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2006 KottaridiBolanaki E., MamurisZ., StathopoulosC.andMarkoulatosP. Molecular phylogeny of VP1, 2A and 2B genes of echovirus isolates: epidemiological linkage and observations on genetic variation 151: 1117-1132. PaximadiE., KarakasiliotisI., MamurisZ., StathopoulosC., KrikelisV. andMarkoulatosP. GenomicanalysisrecombinantSabinclinicalisolatesVirus Genes 32: 203-210. (IF: ) Vourekas A., Kalavrizioti D., Stathopoulos C., (*) and Drainas D. Modulation of catalytic RNA biological activity by small molecule effectors. 6: 971-978. (*)corresponding author Kalavrizioti D. Vourekas A., Stamatopoulou, V., Toumpeki C., Giannouli S., Stathopoulos C., (*) and Drainas D. RNA-mediated therapeutics: from…

Publications 2011-2015

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2012 Balatsos N. A. A., Vlachakis D., Chatzigeorgiou V., Manta S., Komiotis D., Vlassi M. and Stathopoulos C. (*) (*) correspondingauthor Tsikrikonis G., Maniatis A.N., Labrou M., Ntokou E., Michail G., Daponte A., Stathopoulos C., Tsakris A. and Pournaras S. Differences in biofilm formation and virulence genes between clinical and fecal enterococcal isolates of human and animal origin. Microbial Pathogenesis 52: 336-343. Ntokou E., Stathopoulos C., Kristo I., Dimitroulia E.,…

Postdoctoral

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The RNA biology group offers post-doctoral positions in the fields of: Regulation of multiple pathways by tRNA-dependent riboswitches (T-boxes) in pathogens Characterization of essential enzymes with role in mRNA turnover during development The positions are offered based on available funding or after application in National and International agencies funding research. For more information you can check regularly our announcements or you can directly contact Prof C.…

Graduate

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Members of the RNA group participate in teaching of the following MSc graduate programs: University of Patras ·MSc in Biomedical Sciences · MSc in Informatics for Life Sciences ·MSc in Biomedical Engineering · MSc in Medical Physics ·Msc in Public Health ·MSc in Chemical Biology University of Athens ·MSc in Microbial Biotechnology University of Ioannina · MSc in Basic Biomedical Sciences The RNA…

Undergraduate

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Members of the RNA group participate in teaching of the following undergraduate courses which also include lab practicals:Biochemistry I (MED807) Biochemistry II (MED809) Biochemistry III (MED810) Clinical Biochemistry The RNA biology group offers positions to undergraduate students from the School of Medicine, the School of Pharmacy and the Departments of Biology, Chemistry, Biochemistry and Biotechnology, Molecular Biology and Genetics, Biological Applications and…

ncRNAs

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The discovery of non-coding RNAs (ncRNAs) has changed the way we see a broad array of cellular events nowadays in all kingdoms of life. Their complexity in number and types increases as we move up to the evolutionary ladder and many of them specifically target RNA or DNA to inhibit gene function. In eukaryotes, ncRNAs consist of small molecules (<200 nt,…

mRNA

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The control of mRNA lifecycle is critical for the regulation of gene expression. Splicing and Poly(A)-tail addition, mRNA export and translation, every step of mRNA’s life is subject to elaborate control. Sooner or later, every mRNA in all organisms from all kingdoms of life is destined to degrade. For this reason, many mechanisms and factors are devoted to modulate precisely…

tRNA

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Since their first discovery in the early 60’s, research on tRNAs has always been interconnected with the evolution of the genetic code and translation. Today, more than ever, it is evident that tRNA research continues to reveal new and surprising aspects of cellular metabolism. Research on the role of tRNAs as unique adaptor molecules has revolutionized synthetic biology. Moreover, new…