Publications 2001-2005

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  1. Stathopoulos C., Jacquin-Becker C., Becker H.D., Li T., Ambrogelly A., Longman R. and Söll D. Methanococcus jannaschii Prolyl-Cysteinyl-tRNA synthetase possesses overlapping amino acid binding sites. Biochemistry 40: 46-52.
  2. Stathopoulos C., Tekos A., Zarkadis, I. and Drainas D. (2001) Extensive deproteinization of Dictyostelium discoideum RNase Ρ reveals a new catalytic activity. Eur. J. Biochem. 268: 2134-214
  3. Ibba M., Stathopoulos C. and Söll D. . Protein Synthesis: 23 Amino acids and counting. Current Biology 11: 563-565.
  4. Ruan B., Ahel I., Ambrogelly A., Becker H. D., Bunjun S., Feng L., Tumbula D., Ibba M., Korencic D., Kobayashi H., Jacquin-Becker C., Mejlhede N., Min B., Raczniak G., Rinehart J., Stathopoulos, C., Li T. and Söll
  5. StathopoulosC., KimW., LiT., AndersonI., PaliouraS., WhitmanW. andSöllD. Cysteinyl-tRNAsynthetaseisnotessentialfortheviabilitythearcheaonMethanococcusmaripaludis. . USA 98: 14292-14297.


  1. FengL., StathopoulosC., AhelI., MitraA., HartschT., TumbulaD. andSöllD. . Aminoacyl-tRNA formation in the hyperthermophile Themus thermophilus. Extremophiles 6: 167-174.
  2. Jacquin-Becker C., Ahel I., Ambrogelly A., Ruan B. Söll D. and Stathopoulos C. Cysteinyl-tRNA formation and prolyl-tRNA synthetase FEBS Letters 514: 34-36.
  3. Stathopoulos C., Ahel I., Ambrogelly A., Becker H., Bunjun S., Feng L., Herring S., Jacquin-Becker C., Kobayashi H., Korencic D., Krett B., Mejlhede N., Min B., Nakano H., Namgoong S., Polycarpo C., Raczniak G., Rinehart J., Rosas-Sandoval G., Ruan B., Sabina J., Sauerwald A., Toogood H., Tumbula-Hansen D., Ibba M. and Söll D. . Aminoacyl-tRNA synthesis: a post-genome perspective. Cold Spring Harbor Symp. Quant. Biol. Vol. LXVI 175-183.
  4. AhelI., StathopoulosC.,AmbrogellyA., SauerwaldA., ToogoodH., HartschT. andSöllD. Cysteineactivationisaninherentpropertyprolyl-tRNAsynthetases. 277: 34743-34748.
  5. Ambrogelly A., Ahel I., Polycarpo C., Bunjun-Srihari S., Krett B., Jacquin-Becker C., Kohrer C., Stathopoulos C., RajBhandary U.L. and Söll D. Methanocaldococcus jannaschii prolyl-tRNA synthetase charges tRNAPro with cysteine. J. Biol. Chem. 277: 34749-34754.


  1. KalavriziotiD., VourekasA., TekosA., StathopoulosC.andDrainasD. KineticsinhibitionribonucleaseP activity bypeptidyl-transferaseinhibitorsMol30: 9-15. (ΙF: 2.506)
  2. Kamtekar S., Kennedy D.W., Wang J., Stathopoulos C., SöllT.A. (2003) The structural basis of cysteine aminoacylation of tRNAPro by prolyl-tRNA synthetases ProcUSA 100: 1673-1678.


  1. Korencic D., Ahel I., Schelert J., Sacher M., Ruan B., Stathopoulos C., Blum P., Ibba, M. and Söll D. A freestanding proofreading domain isrequired for protein synthesis quality control in archaea. .USA 101: 10260-10265.
  2. Tekos A. (*)Stathopoulos C. (*), Tsambaos D. and Drainas D. (2004) RNase P: a screening system and molecular target for the development of new drugs. Curr. Med. Chem. 11: 2979-2989. (*)Equal contribution, first co-authors


  1. RuanB., BoveeM.L., SacherM., StathopoulosC., PorallaK., FrancklynC.S. andSöllD. (200A unique hydrophobic cluster near the active site contributes to differences of borrelidin inhibition among threonyl-tRNA synthetases. 280: 571-577.
  2. Ambrogelly A., Kamtekar S., Stathopoulos C., Kennedy D. and Söll D. Asymmetrical behavior of archaeal proly-tRNA synthetase FEBSLetters 579: 6017-6022.
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